Dynamic association of capping enzymes with transcribing RNA polymerase II
نویسندگان
چکیده
منابع مشابه
CPD damage recognition by transcribing RNA polymerase II.
Cells use transcription-coupled repair (TCR) to efficiently eliminate DNA lesions such as ultraviolet light-induced cyclobutane pyrimidine dimers (CPDs). Here we present the structure-based mechanism for the first step in eukaryotic TCR, CPD-induced stalling of RNA polymerase (Pol) II. A CPD in the transcribed strand slowly passes a translocation barrier and enters the polymerase active site. T...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2000
ISSN: 0890-9369
DOI: 10.1101/gad.836300